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Love smoking that Mary Jane? Well, new research says that your passion for rolling up that five-leafed friend might be inside your nether regions if you´re a dude, bro.

University of Southern California (USC) researchers wrote within the peer-reviewed journal of the American Cancer Society that they have linked marijuana smoking for an increased chance of developing testicular cancer.

Testicular cancer is most commonly diagnosed in males between the ages of 15 and 45, and malignancy the tendency for cancerous tumors to spread uncontrollably is increasingly common in the condition.

Researchers decided to use science to determine whether recreational drug use had anything to use the increasing frequency of those potentially deadly tumors.

Victoria Cortessis, MSPH, PhD, assistant professor of preventive medicine in the Keck School of Medicine of USC in Los Angeles and colleagues looked at self-reported good reputation for recreational drug use in 163 teenagers who had been identified as having testicular cancer. The team compared the men’s data with this of 292 healthy men of the same age and race.

The researchers found that men who were built with a good reputation for using marijuana were two times as likely to have subtypes of testicular cancer called non-seminoma in addition to mixed germ cell tumors. These tumors typically exist in younger men and have a worse prognosis than the seminoma subtype.

Through the study, the researchers could confirm the findings of two previous reports within the American Cancer Society´s official journal Cancer by linking marijuana use with testicular cancer.

“We do not know what marijuana triggers within the testis that may result in carcinogenesis, although we speculate that it may be acting through the endocannabinoid system the cellular network that responds towards the active ingredient in marijuana since this technique can make a difference in the formation of sperm,” Cortessis said in a press release.

The latest research surprisingly discovered that a history of using cocaine were built with a reduced risk of both subtypes of testicular cancer. However, this doesn’t mean the findings should give you the green light to put on the bong and get the blow.

The findings suggest that men with testicular cancer are merely reluctant to stop as much information about their past record with recreational drug use as the other 292 healthy candidates.

The authors of the study suspect that the ivory line drug might actually kill sperm-producing germ cells, which has been observed in experiments with laboratory animals before.

“If this sounds like correct, then ‘prevention’ will come in a high price,” Cortessis said inside a pr release. “Although germ cells can not develop cancer if they’re first destroyed, fertility would also be impaired. Since this is the very first study in which an association between cocaine use minimizing testis cancer risk is noted, additional epidemiological studies are required to validate the outcomes.”